Our Science

Current ADCs are Limited to Targets with High Expression and Rapid Internalization

Current ADCs are Limited to Targets
with High Expression and Rapid Internalization

What Are ADCs?

Benefits of Improving ADCs

Peptide-Antibody Chimeras

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Lysosome-Directed ADCs Improve Payload Delivery.

We build modular antibodies that interact with the cellular trafficking machinery to improve internalization and payload release. This approach enables improved efficacy and safety for existing targets while unlocking novel targets.

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The Future of ADCs

With enhanced tissue-selective payload delivery, the field has opportunities to improve efficacy and safety: same efficacy with lower doses, as well as improved safety with lower potency payloads.

Partner With Us

Our scaffolds override subcellular trafficking patterns for a target and improve ADC delivery to the lysosome. Reach out to learn more.